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Ajinomoto Bio-Pharma Achieve Commercial-scale Continuous Manufacturing!
8 November 2021
Chemtrix BV & Ajinomoto Bio-Pharma NV are proud to announce their collaboration on a commercial continuous manufacturing project!
Faced with a request to scale-up a challenging multi-step process, initially to 10's kg & subsequently to multi-tonnes per week, Ajinomoto Bio-Pharma chose the Plantrix MR555 flow reactor to be at the heart of the multi-purpose continuous flow system. Producing >500 MT of material in its first year of operation!
To achieve this, Ajinomoto Bio-Pharma's Team of chemists & engineers developed a continuous flow process that increased process safety & reduced the number of unit operations, leading to;
- Doubling of annual throughput cf. dedicated batch unit
- Reduction in the overall carbon footprint by 30%
- Target price manufacturing
As Dr. Eric De Vos say's:
'We have been very eager to implement our continuous flow design & our Teams have gained significant knowledge around this platform which will facilitate changeovers & modifications for future Client programs. Adopting continuous flow technology is instrumental to Ajinomoto Bio-Pharma's expansion strategy.'
To learn more about this case & planned next steps, download the reference case!
For further information contact:
|Dr. Eric De Vos||Dr. Charlotte Wiles|
|Ajinomoto Bio-Pharma||Chemtrix BV|
|VP Global Innovation & Director of R&D (Europe)||CEO|
About Ajinomoto Bio-Pharma
Ajinomoto Bio-Pharma is a leading global business partner for Phramaceutical APIs & Intermediates, amino acids, agrochemicals & botanical extractions. The Company is committed to supplying the highest quality products & services, based on their reliable & flexible production, innovative research & market responsiveness. www.ajibio-pharma.com
Chemtrix BV offers a scalable flow reactor portfolio that affords researchers & industrialists the tools required to harness the advantages of primary continuous manufacturing. We combine expertise in the field of mechanical engineering, chemical engineering & chemistry to help our customers to benefit from the advantages that flow chemistry brings. Our expertise enables us to offer scalable & flexible flow chemistry solutions, focussing on delivering our Customers higher profits by accessing new chemical possibilities via a safe & reliable scale-up from lab to production-scale. Working closely with academia & industry, we work to change the way that chemical processes are developed & implemented. Our global user base spans research institutes & government laboratories to leaders in the fine chemical, specialty & pharmaceutical industries. www.chemtrix.com