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Ajinomoto Bio-Pharma Achieve Commercial-scale Continuous Manufacturing!

8 November 2021

Chemtrix BV & Ajinomoto Bio-Pharma NV are proud to announce their collaboration on a commercial continuous manufacturing project! 

Faced with a request to scale-up a challenging multi-step process, initially to 10's kg & subsequently to multi-tonnes per week, Ajinomoto Bio-Pharma chose the Plantrix MR555 flow reactor to be at the heart of the multi-purpose continuous flow system.  Producing >500 MT of material in its first year of operation!  

To achieve this, Ajinomoto Bio-Pharma's Team of chemists & engineers developed a continuous flow process that increased process safety & reduced the number of unit operations, leading to;

  • Doubling of annual throughput cf. dedicated batch unit
  • Reduction in the overall carbon footprint by 30%
  • Target price manufacturing

As Dr. Eric De Vos say's:

'We have been very eager to implement our continuous flow design & our Teams have gained significant knowledge around this platform which will facilitate changeovers & modifications for future Client programs.  Adopting continuous flow technology is instrumental to Ajinomoto Bio-Pharma's expansion strategy.'

To learn more about this case & planned next steps, download the reference case!

For further information contact:

Dr. Eric De Vos                                                             Dr. Charlotte Wiles
Ajinomoto Bio-Pharma Chemtrix BV
VP Global Innovation & Director of R&D (Europe) CEO                            

About Ajinomoto Bio-Pharma
Ajinomoto Bio-Pharma is a leading global business partner for Phramaceutical APIs & Intermediates, amino acids, agrochemicals & botanical extractions.  The Company is committed to supplying the highest quality products & services, based on their reliable & flexible production, innovative research & market responsiveness.

About Chemtrix
Chemtrix BV offers a scalable flow reactor portfolio that affords researchers & industrialists the tools required to harness the advantages of primary continuous manufacturing.  We combine expertise in the field of mechanical engineering, chemical engineering & chemistry to help our customers to benefit from the advantages that flow chemistry brings.  Our expertise enables us to offer scalable & flexible flow chemistry solutions, focussing on delivering our Customers higher profits by accessing new chemical possibilities via a safe & reliable scale-up from lab to production-scale.  Working closely with academia & industry, we work to change the way that chemical processes are developed & implemented.  Our global user base spans research institutes & government laboratories to leaders in the fine chemical, specialty & pharmaceutical industries.

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